1,555 research outputs found
Excitable human dynamics driven by extrinsic events in massive communities
Using empirical data from a social media site (Twitter) and on trading
volumes of financial securities, we analyze the correlated human activity in
massive social organizations. The activity, typically excited by real-world
events and measured by the occurrence rate of international brand names and
trading volumes, is characterized by intermittent fluctuations with bursts of
high activity separated by quiescent periods. These fluctuations are broadly
distributed with an inverse cubic tail and have long-range temporal
correlations with a power spectrum. We describe the activity by a
stochastic point process and derive the distribution of activity levels from
the corresponding stochastic differential equation. The distribution and the
corresponding power spectrum are fully consistent with the empirical
observations.Comment: 9 pages, 3 figure
Female gender increases stiffness of elastic but not of muscular arteries in type I diabetic patients.
The reason for the particularly increased risk for cardiovascular complications in diabetic women is still unclear. We have previously found decreased distensibility of elastic arteries in type I diabetic women, indicating increased cardiac load, not seen in type I diabetic men, which might be one contributing factor. Whether the effect of gender is different in muscular arteries in type I diabetic patients has not been assessed. As estimates of arterial distensibility we measured stiffness (beta) and pressure strain elastic modulus (Ep) in the muscular common femoral artery using echo-tracking sonography in 30 women (mean age 34 years, range 20-61) and 26 men (mean age 38 years, range 22-56) with type I diabetes. The results were compared with those of 89 healthy individuals of corresponding age and gender and with previously published results from elastic arteries in these patients obtained at the same occasion. The internal common femoral diameter was significantly decreased in both diabetic men and women. In sharp contrast to the highly significant decreased distensibility of the elastic abdominal aorta and common carotid artery in the type I diabetic women, the distensibility of the common femoral artery did not clearly differ between patients and controls, neither for women nor for men. Thus, the gender difference in changes of arterial distensibility found in elastic arteries was absent or far less obvious in the femoral artery. In conclusion, female gender seems to affect the mechanical properties of elastic, but not of large muscular arteries in type I diabetic patients. Thus, putative gender differences in arterial changes in type I diabetes are to be sought in elastic rather than muscular arteries
Determination of retained tritium from ILW dust particles in JET
Quantitative tritium inventory in dust particles from campaigns in the JET tokamak with the carbon wall (2007-2009) and the ITER-like wall (ILW 2011-2012) were determined by the liquid scintillation counter and the full combustion method. A feature of this full combustion method is that dust particles were covered by a tin (Sn) which reached 2100 K during combustion under oxygen flow. The specific tritium inventory for samples from JET with carbon and with metal walls was measured and found to be similar. However, the total tritium inventory in dust particles from the ILW experiment was significantly smaller in comparison to the carbon wall due to the lower amount of dust particles generated in the presence of metal walls.Peer reviewe
Modelling of the effect of ELMs on fuel retention at the bulk W divertor of JET
Effect of ELMs on fuel retention at the bulk W target of JET ITER-Like Wall was studied with multi-scale calculations. Plasma input parameters were taken from ELMy H-mode plasma experiment. The energetic intra-ELM fuel particles get implanted and create near-surface defects up to depths of few tens of nm, which act as the main fuel trapping sites during ELMs. Clustering of implantation-induced vacancies were found to take place. The incoming flux of inter-ELM plasma particles increases the different filling levels of trapped fuel in defects. The temperature increase of the W target during the pulse increases the fuel detrapping rate. The inter-ELM fuel particle flux refills the partially emptied trapping sites and fills new sites. This leads to a competing effect on the retention and release rates of the implanted particles. At high temperatures the main retention appeared in larger vacancy clusters due to increased clustering rate.Peer reviewe
Reduced Aortic Wall Stress in Diabetes Mellitus
ObjectiveMost risk factors are similar for abdominal aortic aneurysm (AAA) and atherosclerosis, e.g. smoking, male gender, age, high blood pressure, hyperlipidemia. Diabetes mellitus however, is a risk factor for atherosclerosis, but diabetic patients seldom develop AAA. The reason for this discrepancy is unknown. Increased aortic wall stress seems to be an etiologic factor in the formation, growth and rupture of AAA in man. The aim of our study was to study the wall stress in the abdominal aorta in diabetic patients compared with healthy controls.Methods39 patients with diabetes mellitus and 46 age – and sex matched healthy subjects were examined with B-mode ultrasound to determine the lumen diameter (LD) and intima-media thickness (IMT) in the abdominal aorta (AA) and the common carotid artery (CCA). Diastolic blood pressure (DBP) was measured non-invasively in the brachial artery. LaPlace law was used to calculate circumferential wall stress.ResultsAge, DBP, and LD in the abdominal aorta were not significantly different in the diabetic patients compared to controls. IMT in the AA was larger in the diabetic patients, 0.89±0.17 vs 0.73±0.11mm (p<.001). Accordingly aortic wall stress was reduced in the diabetics, 7.8±1.7×105 vs 9.7±1.9×105dynes/cm2 (p<.001).ConclusionsWall stress in the abdominal aorta is reduced in diabetes mellitus. This is mainly due to a thicker aortic wall compared to healthy controls. The reduced aortic wall stress coincides with the fact that epidemiological studies have shown a decreased risk of aneurysm development in diabetic patients
Sink strength simulations using the Monte Carlo method : Applied to spherical traps
The sink strength is an important parameter for the mean-field rate equations to simulate temporal changes in the micro-structure of materials. However, there are noteworthy discrepancies between sink strengths obtained by the Monte Carlo and analytical methods. In this study, we show the reasons for these differences. We present the equations to estimate the statistical error for sink strength calculations and show the way to determine the sink strengths for multiple traps. We develop a novel, very fast Monte Carlo method to obtain sink strengths. The results show that, in addition to the well-known sink strength dependence of the trap concentration, trap radius and the total sink strength, the sink strength also depends on the defect diffusion jump length and the total trap volume fraction. Taking these factors into account, allows us to obtain a very accurate analytic expression for the sink strength of spherical traps. (C) 2017 Elsevier B. V. All rights reserved.Peer reviewe
Is There a Relationship between Abdominal Aortic Aneurysms and Alpha1-antitrypsin Deficiency (PiZ)?
AbstractObjective:to determine if the frequency of α1AT deficiency (PiZ) is increased in patients with abdominal aortic aneurysm (AAA), and, to investigate whether aneurysmal stiffness and other clinical characteristics differ in AAA patients with and without α1AT deficiency.Methods:we identified α1AT-deficient individuals by a monoclonal-antibody ELISA technique, in 102 consecutive patients with AAA. Positive ELISA samples were further phenotyped by isoelectric focusing to differentiate between the heterozygosity (PiZ) and homozygosity (PiZZ) state. Aneurysmal diameter and stiffness was measured using echotracking sonography and blood pressure measurements.Results:the frequency of heterozygous α1AT deficiency (PiZ) in patients with AAA was similar to that in the general population (6.8% and 4.7%, respectively,p>0.3). The frequency of popliteal and femoral aneurysm was similar in male PiZ-carriers and non-carriers with AAA, as were age at diagnosis of AAA, aneurysmal diameter, aneurysmal stiffness, and presence of factors that may be associated with AAA (i.e. smoking, hypertension, diabetes mellitus, and family history of AAA). Occurrence of ischaemic heart disease was more frequent in male non-PiZ-carriers than in male PiZ-carriers with AAA (p=0.03).Conclusions:the frequency of α1AT deficiency (PiZ) was not increased in our series of patients with AAA and patients in whom the two disorders coexisted did not appear to have different clinical characteristics except for the lower occurrence of ischaemic heart disease among the PiZ-carriers
Long-term fuel retention and release in JET ITER-Like Wall at ITER-relevant baking temperatures
The fuel outgassing efficiency from plasma-facing components exposed in JET-ILW has been
studied at ITER-relevant baking temperatures. Samples retrieved from the W divertor and
Be main chamber were annealed at 350 and 240 °C, respectively. Annealing was performed
with thermal desoprtion spectrometry (TDS) for 0, 5 and 15 h to study the deuterium removal
effectiveness at the nominal baking temperatures. The remained fraction was determined by
emptying the samples fully of deuterium by heating W and Be samples up to 1000 and 775 °C,
respectively. Results showed the deposits in the divertor having an increasing effect to the
remaining retention at temperatures above baking. Highest remaining fractions 54 and 87%
were observed with deposit thicknesses of 10 and 40 μm, respectively. Substantially high
fractions were obtained in the main chamber samples from the deposit-free erosion zone of
the limiter midplane, in which the dominant fuel retention mechanism is via implantation:
15 h annealing resulted in retained deuterium higher than 90%. TDS results from the divertor
were simulated with TMAP7 calculations. The spectra were modelled with three deuterium
activation energies resulting in good agreement with the experimentsEURATOM 63305
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